Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
Identifieur interne : 002874 ( Main/Exploration ); précédent : 002873; suivant : 002875Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
Auteurs : David D. Bowtell ; Steffen Böhm ; Ahmed A. Ahmed ; Paul-Joseph Aspuria ; Robert C. Bast ; Valerie Beral ; Jonathan S. Berek ; Michael J. Birrer ; Sarah Blagden ; Michael A. Bookman ; James Brenton ; Katherine B. Chiappinelli ; Filipe Correia Martins ; George Coukos ; Ronny Drapkin ; Richard Edmondson ; Christina Fotopoulou ; Hani Gabra ; Jérôme Galon ; Charlie Gourley ; Valerie Heong ; David G. Huntsman ; Marcin Iwanicki ; Beth Y. Karlan ; Allyson Kaye ; Ernst Lengyel ; Douglas A. Levine ; Karen H. Lu ; Iain A. Mcneish ; Usha Menon ; Steve A. Narod ; Brad H. Nelson ; Kenneth P. Nephew ; Paul Pharoah ; Daniel J. Powell ; Pilar Ramos ; Iris L. Romero ; Clare L. Scott ; Anil K. Sood ; Euan A. Stronach ; Frances R. BalkwillSource :
- Nature reviews. Cancer [ 1474-175X ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Cystadénocarcinome séreux, Tumeurs de l'ovaire.
- mortalité : Cystadénocarcinome séreux, Tumeurs de l'ovaire.
- Cystadénocarcinome séreux, Femelle, Grading des tumeurs, Humains, Pronostic, Taux de survie, Tumeurs de l'ovaire.
English descriptors
- KwdEn :
- MESH :
- mortality : Cystadenocarcinoma, Serous, Ovarian Neoplasms.
- pathology : Cystadenocarcinoma, Serous, Ovarian Neoplasms.
- prevention & control : Cystadenocarcinoma, Serous, Ovarian Neoplasms.
- Female, Humans, Neoplasm Grading, Prognosis, Survival Rate.
Abstract
High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of ovarian cancer deaths, and overall survival has not changed significantly for several decades. In this Opinion article, we outline a set of research priorities that we believe will reduce incidence and improve outcomes for women with this disease. This ‘roadmap’ for HGSOC was determined after extensive discussions at an Ovarian Cancer Action meeting in January 2015.
Url:
DOI: 10.1038/nrc4019
PubMed: 26493647
PubMed Central: 4892184
Affiliations:
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Bowtell</name></author><author><name sortKey="Bohm, Steffen" sort="Bohm, Steffen" uniqKey="Bohm S" first="Steffen" last="Böhm">Steffen Böhm</name></author><author><name sortKey="Ahmed, Ahmed A" sort="Ahmed, Ahmed A" uniqKey="Ahmed A" first="Ahmed A." last="Ahmed">Ahmed A. Ahmed</name></author><author><name sortKey="Aspuria, Paul Joseph" sort="Aspuria, Paul Joseph" uniqKey="Aspuria P" first="Paul-Joseph" last="Aspuria">Paul-Joseph Aspuria</name></author><author><name sortKey="Bast, Robert C" sort="Bast, Robert C" uniqKey="Bast R" first="Robert C." last="Bast">Robert C. Bast</name></author><author><name sortKey="Beral, Valerie" sort="Beral, Valerie" uniqKey="Beral V" first="Valerie" last="Beral">Valerie Beral</name></author><author><name sortKey="Berek, Jonathan S" sort="Berek, Jonathan S" uniqKey="Berek J" first="Jonathan S." last="Berek">Jonathan S. Berek</name></author><author><name sortKey="Birrer, Michael J" sort="Birrer, Michael J" uniqKey="Birrer M" first="Michael J." last="Birrer">Michael J. Birrer</name></author><author><name sortKey="Blagden, Sarah" sort="Blagden, Sarah" uniqKey="Blagden S" first="Sarah" last="Blagden">Sarah Blagden</name></author><author><name sortKey="Bookman, Michael A" sort="Bookman, Michael A" uniqKey="Bookman M" first="Michael A." last="Bookman">Michael A. Bookman</name></author><author><name sortKey="Brenton, James" sort="Brenton, James" uniqKey="Brenton J" first="James" last="Brenton">James Brenton</name></author><author><name sortKey="Chiappinelli, Katherine B" sort="Chiappinelli, Katherine B" uniqKey="Chiappinelli K" first="Katherine B." last="Chiappinelli">Katherine B. Chiappinelli</name></author><author><name sortKey="Martins, Filipe Correia" sort="Martins, Filipe Correia" uniqKey="Martins F" first="Filipe Correia" last="Martins">Filipe Correia Martins</name></author><author><name sortKey="Coukos, George" sort="Coukos, George" uniqKey="Coukos G" first="George" last="Coukos">George Coukos</name></author><author><name sortKey="Drapkin, Ronny" sort="Drapkin, Ronny" uniqKey="Drapkin R" first="Ronny" last="Drapkin">Ronny Drapkin</name></author><author><name sortKey="Edmondson, Richard" sort="Edmondson, Richard" uniqKey="Edmondson R" first="Richard" last="Edmondson">Richard Edmondson</name></author><author><name sortKey="Fotopoulou, Christina" sort="Fotopoulou, Christina" uniqKey="Fotopoulou C" first="Christina" last="Fotopoulou">Christina Fotopoulou</name></author><author><name sortKey="Gabra, Hani" sort="Gabra, Hani" uniqKey="Gabra H" first="Hani" last="Gabra">Hani Gabra</name></author><author><name sortKey="Galon, Jerome" sort="Galon, Jerome" uniqKey="Galon J" first="Jérôme" last="Galon">Jérôme Galon</name></author><author><name sortKey="Gourley, Charlie" sort="Gourley, Charlie" uniqKey="Gourley C" first="Charlie" last="Gourley">Charlie Gourley</name></author><author><name sortKey="Heong, Valerie" sort="Heong, Valerie" uniqKey="Heong V" first="Valerie" last="Heong">Valerie Heong</name></author><author><name sortKey="Huntsman, David G" sort="Huntsman, David G" uniqKey="Huntsman D" first="David G." last="Huntsman">David G. Huntsman</name></author><author><name sortKey="Iwanicki, Marcin" sort="Iwanicki, Marcin" uniqKey="Iwanicki M" first="Marcin" last="Iwanicki">Marcin Iwanicki</name></author><author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name></author><author><name sortKey="Kaye, Allyson" sort="Kaye, Allyson" uniqKey="Kaye A" first="Allyson" last="Kaye">Allyson Kaye</name></author><author><name sortKey="Lengyel, Ernst" sort="Lengyel, Ernst" uniqKey="Lengyel E" first="Ernst" last="Lengyel">Ernst Lengyel</name></author><author><name sortKey="Levine, Douglas A" sort="Levine, Douglas A" uniqKey="Levine D" first="Douglas A." last="Levine">Douglas A. Levine</name></author><author><name sortKey="Lu, Karen H" sort="Lu, Karen H" uniqKey="Lu K" first="Karen H." last="Lu">Karen H. Lu</name></author><author><name sortKey="Mcneish, Iain A" sort="Mcneish, Iain A" uniqKey="Mcneish I" first="Iain A." last="Mcneish">Iain A. Mcneish</name></author><author><name sortKey="Menon, Usha" sort="Menon, Usha" uniqKey="Menon U" first="Usha" last="Menon">Usha Menon</name></author><author><name sortKey="Narod, Steve A" sort="Narod, Steve A" uniqKey="Narod S" first="Steve A." last="Narod">Steve A. Narod</name></author><author><name sortKey="Nelson, Brad H" sort="Nelson, Brad H" uniqKey="Nelson B" first="Brad H." last="Nelson">Brad H. Nelson</name></author><author><name sortKey="Nephew, Kenneth P" sort="Nephew, Kenneth P" uniqKey="Nephew K" first="Kenneth P." last="Nephew">Kenneth P. Nephew</name></author><author><name sortKey="Pharoah, Paul" sort="Pharoah, Paul" uniqKey="Pharoah P" first="Paul" last="Pharoah">Paul Pharoah</name></author><author><name sortKey="Powell, Daniel J" sort="Powell, Daniel J" uniqKey="Powell D" first="Daniel J." last="Powell">Daniel J. Powell</name></author><author><name sortKey="Ramos, Pilar" sort="Ramos, Pilar" uniqKey="Ramos P" first="Pilar" last="Ramos">Pilar Ramos</name></author><author><name sortKey="Romero, Iris L" sort="Romero, Iris L" uniqKey="Romero I" first="Iris L." last="Romero">Iris L. Romero</name></author><author><name sortKey="Scott, Clare L" sort="Scott, Clare L" uniqKey="Scott C" first="Clare L." last="Scott">Clare L. Scott</name></author><author><name sortKey="Sood, Anil K" sort="Sood, Anil K" uniqKey="Sood A" first="Anil K." last="Sood">Anil K. Sood</name></author><author><name sortKey="Stronach, Euan A" sort="Stronach, Euan A" uniqKey="Stronach E" first="Euan A." last="Stronach">Euan A. Stronach</name></author><author><name sortKey="Balkwill, Frances R" sort="Balkwill, Frances R" uniqKey="Balkwill F" first="Frances R." last="Balkwill">Frances R. Balkwill</name></author></analytic><series><title level="j">Nature reviews. Cancer</title><idno type="ISSN">1474-175X</idno><idno type="eISSN">1474-1768</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cystadenocarcinoma, Serous (mortality)</term><term>Cystadenocarcinoma, Serous (pathology)</term><term>Cystadenocarcinoma, Serous (prevention & control)</term><term>Female</term><term>Humans</term><term>Neoplasm Grading</term><term>Ovarian Neoplasms (mortality)</term><term>Ovarian Neoplasms (pathology)</term><term>Ovarian Neoplasms (prevention & control)</term><term>Prognosis</term><term>Survival Rate</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Cystadénocarcinome séreux ()</term><term>Cystadénocarcinome séreux (anatomopathologie)</term><term>Cystadénocarcinome séreux (mortalité)</term><term>Femelle</term><term>Grading des tumeurs</term><term>Humains</term><term>Pronostic</term><term>Taux de survie</term><term>Tumeurs de l'ovaire ()</term><term>Tumeurs de l'ovaire (anatomopathologie)</term><term>Tumeurs de l'ovaire (mortalité)</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Cystadénocarcinome séreux</term><term>Tumeurs de l'ovaire</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Cystadenocarcinoma, Serous</term><term>Ovarian Neoplasms</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Cystadénocarcinome séreux</term><term>Tumeurs de l'ovaire</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Cystadenocarcinoma, Serous</term><term>Ovarian Neoplasms</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cystadenocarcinoma, Serous</term><term>Ovarian Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Neoplasm Grading</term><term>Prognosis</term><term>Survival Rate</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Cystadénocarcinome séreux</term><term>Femelle</term><term>Grading des tumeurs</term><term>Humains</term><term>Pronostic</term><term>Taux de survie</term><term>Tumeurs de l'ovaire</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of ovarian cancer deaths, and overall survival has not changed significantly for several decades. In this Opinion article, we outline a set of research priorities that we believe will reduce incidence and improve outcomes for women with this disease. This ‘roadmap’ for HGSOC was determined after extensive discussions at an Ovarian Cancer Action meeting in January 2015.</p></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Ahmed, Ahmed A" sort="Ahmed, Ahmed A" uniqKey="Ahmed A" first="Ahmed A." last="Ahmed">Ahmed A. Ahmed</name><name sortKey="Aspuria, Paul Joseph" sort="Aspuria, Paul Joseph" uniqKey="Aspuria P" first="Paul-Joseph" last="Aspuria">Paul-Joseph Aspuria</name><name sortKey="Balkwill, Frances R" sort="Balkwill, Frances R" uniqKey="Balkwill F" first="Frances R." last="Balkwill">Frances R. Balkwill</name><name sortKey="Bast, Robert C" sort="Bast, Robert C" uniqKey="Bast R" first="Robert C." last="Bast">Robert C. Bast</name><name sortKey="Beral, Valerie" sort="Beral, Valerie" uniqKey="Beral V" first="Valerie" last="Beral">Valerie Beral</name><name sortKey="Berek, Jonathan S" sort="Berek, Jonathan S" uniqKey="Berek J" first="Jonathan S." last="Berek">Jonathan S. Berek</name><name sortKey="Birrer, Michael J" sort="Birrer, Michael J" uniqKey="Birrer M" first="Michael J." last="Birrer">Michael J. Birrer</name><name sortKey="Blagden, Sarah" sort="Blagden, Sarah" uniqKey="Blagden S" first="Sarah" last="Blagden">Sarah Blagden</name><name sortKey="Bohm, Steffen" sort="Bohm, Steffen" uniqKey="Bohm S" first="Steffen" last="Böhm">Steffen Böhm</name><name sortKey="Bookman, Michael A" sort="Bookman, Michael A" uniqKey="Bookman M" first="Michael A." last="Bookman">Michael A. Bookman</name><name sortKey="Bowtell, David D" sort="Bowtell, David D" uniqKey="Bowtell D" first="David D." last="Bowtell">David D. Bowtell</name><name sortKey="Brenton, James" sort="Brenton, James" uniqKey="Brenton J" first="James" last="Brenton">James Brenton</name><name sortKey="Chiappinelli, Katherine B" sort="Chiappinelli, Katherine B" uniqKey="Chiappinelli K" first="Katherine B." last="Chiappinelli">Katherine B. Chiappinelli</name><name sortKey="Coukos, George" sort="Coukos, George" uniqKey="Coukos G" first="George" last="Coukos">George Coukos</name><name sortKey="Drapkin, Ronny" sort="Drapkin, Ronny" uniqKey="Drapkin R" first="Ronny" last="Drapkin">Ronny Drapkin</name><name sortKey="Edmondson, Richard" sort="Edmondson, Richard" uniqKey="Edmondson R" first="Richard" last="Edmondson">Richard Edmondson</name><name sortKey="Fotopoulou, Christina" sort="Fotopoulou, Christina" uniqKey="Fotopoulou C" first="Christina" last="Fotopoulou">Christina Fotopoulou</name><name sortKey="Gabra, Hani" sort="Gabra, Hani" uniqKey="Gabra H" first="Hani" last="Gabra">Hani Gabra</name><name sortKey="Galon, Jerome" sort="Galon, Jerome" uniqKey="Galon J" first="Jérôme" last="Galon">Jérôme Galon</name><name sortKey="Gourley, Charlie" sort="Gourley, Charlie" uniqKey="Gourley C" first="Charlie" last="Gourley">Charlie Gourley</name><name sortKey="Heong, Valerie" sort="Heong, Valerie" uniqKey="Heong V" first="Valerie" last="Heong">Valerie Heong</name><name sortKey="Huntsman, David G" sort="Huntsman, David G" uniqKey="Huntsman D" first="David G." last="Huntsman">David G. Huntsman</name><name sortKey="Iwanicki, Marcin" sort="Iwanicki, Marcin" uniqKey="Iwanicki M" first="Marcin" last="Iwanicki">Marcin Iwanicki</name><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name><name sortKey="Kaye, Allyson" sort="Kaye, Allyson" uniqKey="Kaye A" first="Allyson" last="Kaye">Allyson Kaye</name><name sortKey="Lengyel, Ernst" sort="Lengyel, Ernst" uniqKey="Lengyel E" first="Ernst" last="Lengyel">Ernst Lengyel</name><name sortKey="Levine, Douglas A" sort="Levine, Douglas A" uniqKey="Levine D" first="Douglas A." last="Levine">Douglas A. Levine</name><name sortKey="Lu, Karen H" sort="Lu, Karen H" uniqKey="Lu K" first="Karen H." last="Lu">Karen H. Lu</name><name sortKey="Martins, Filipe Correia" sort="Martins, Filipe Correia" uniqKey="Martins F" first="Filipe Correia" last="Martins">Filipe Correia Martins</name><name sortKey="Mcneish, Iain A" sort="Mcneish, Iain A" uniqKey="Mcneish I" first="Iain A." last="Mcneish">Iain A. Mcneish</name><name sortKey="Menon, Usha" sort="Menon, Usha" uniqKey="Menon U" first="Usha" last="Menon">Usha Menon</name><name sortKey="Narod, Steve A" sort="Narod, Steve A" uniqKey="Narod S" first="Steve A." last="Narod">Steve A. Narod</name><name sortKey="Nelson, Brad H" sort="Nelson, Brad H" uniqKey="Nelson B" first="Brad H." last="Nelson">Brad H. Nelson</name><name sortKey="Nephew, Kenneth P" sort="Nephew, Kenneth P" uniqKey="Nephew K" first="Kenneth P." last="Nephew">Kenneth P. Nephew</name><name sortKey="Pharoah, Paul" sort="Pharoah, Paul" uniqKey="Pharoah P" first="Paul" last="Pharoah">Paul Pharoah</name><name sortKey="Powell, Daniel J" sort="Powell, Daniel J" uniqKey="Powell D" first="Daniel J." last="Powell">Daniel J. Powell</name><name sortKey="Ramos, Pilar" sort="Ramos, Pilar" uniqKey="Ramos P" first="Pilar" last="Ramos">Pilar Ramos</name><name sortKey="Romero, Iris L" sort="Romero, Iris L" uniqKey="Romero I" first="Iris L." last="Romero">Iris L. Romero</name><name sortKey="Scott, Clare L" sort="Scott, Clare L" uniqKey="Scott C" first="Clare L." last="Scott">Clare L. Scott</name><name sortKey="Sood, Anil K" sort="Sood, Anil K" uniqKey="Sood A" first="Anil K." last="Sood">Anil K. Sood</name><name sortKey="Stronach, Euan A" sort="Stronach, Euan A" uniqKey="Stronach E" first="Euan A." last="Stronach">Euan A. Stronach</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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